Continuing from the part-1 of this series
where we learned the types of diabetes, how they develop and what are the risk
factors (link below). In this part, 2nd and last in this series, we will learn how diabetes harms us, is it just the increased
glucose or it means something else as well.
http://simplefiedscience.blogspot.in/2014/01/diabetes-prevention-and-management-by.html
Thus, next time when you see someone reacting to high glucose level in a random blood test in disbelief, anguish, anxiety, worry and other emotional expressions, you know what we must do as an individual and as a society!
http://simplefiedscience.blogspot.in/2014/01/diabetes-prevention-and-management-by.html
Come to think of it, how diabetes harms our
body is yet another area where general population is found misinformed and
misguided. There is much more than sugar in the urine, sweating, trembling of
hands and legs, and usual anxiety in diabetes. The increased glucose level in
the blood creates havoc for the cells in our body. It deregulates the normal
metabolism and function of the organs including liver, heart, kidney, eyes,
brain, lungs, blood capillaries and their cells.
Even though our cells are being severely
affected and damaged by increased sugar in the blood, we do not realize this
until it is too late. Initially, in type 2 diabetes, with little increase in
the blood sugar our body tries to adjust by increasing the insulin level.
Slowly, it reaches a point where even several fold increase in insulin,
hyper-insulinemia, is also not effective to down regulate glucose level. And
because insulin also helps in increased fatty acid synthesis, cell growth and
many other physiological role, the enhanced levels of insulin may expose the
body to many other pathological conditions such as metabolic deregulation,
obesity, heart diseases, cancer and so on.
Image curtesy: http://www.lef.org/
After a while insulin level tapers down
leading to full-blown diabetes where there is no regulation of blood glucose,
whatsoever. At this stage gluco-meter readings come more than 400mg/dL.
The vessels that carry the blood get affected
first leading to macro- and micro-angiopathy including endothelial dysfunction,
arteriosclerosis and angiogenesis, neuropathy leading to loss in sensation and
nerve conduction, nephropathy leading to kidney failure, occulopathy such as
diabetic retinopathy, glaucoma and cataract development in eye lens. Besides
these, the frequent glucose up-regulation (hyperglycemia) and down-regulation
(hypoglycemia) creates problem to the brain functioning leading to
hallucinations, disorientation, depression and other problems.
Cartoon curtesy: oldsailor2007.blogspot.com
Although early diagnosis would lead to better
management of the diabetes, being older or newer disease is not as important as
how well or poorly it has been managed. Even if diabetes is diagnosed early, if
not managed well with proper diet, exercise and healthy lifestyle, the patients
suffer more mortality and morbidity.
To be a diabetes free society it is as much
an individual problem as a social problem. Many epidemiological studies
indicate that society plays greater role in how and which disease spreads in
its people.
Image curtesy: (Diabetics Friends Society) http://youngleaders.idf.org/
If a society has good attitude towards
healthy eating and living, and educational and awareness programs to educate
its people, the individuals could benefit and protect themselves from many
diseases, including diabetes.
Image Curtesy: www.h3daily.com/
What is good eating and living attitude? To
recognize how much calorie one needs to stay active and fit, to know which food
has roughly how much calories, to be aware that in the comfort and luxury
seeking society physical activity is equally or rather highly important factor
to stay well and free of diseases. Individual eating and living approach will
have better effect on overall behavior of the society towards how it protects
its people and tackles the lifestyle diseases such as obesity and diabetes.
Image curtesy:http://lankaspice.wordpress.com
Thus, next time when you see someone reacting to high glucose level in a random blood test in disbelief, anguish, anxiety, worry and other emotional expressions, you know what we must do as an individual and as a society!
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Very nice information. Thank you for your explanation. Everyone should aware about this disease. Knowing the risk of this disease, we should have done something to prevent and reduce it. diabetescentrale.nl can help
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